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Birth defects which have been documented following Accutane exposure include abnormalities of the face, eyes, ears, skull, central nervous system, cardiovascular system, and thymus and parathyroid glands. Cases of IQ scores less than 85 with or without other abnormalities have been reported. There is an increased risk of spontaneous abortion, and premature births have been reported.
It was first marketed by Eli Lilly and Company, and it is today commonly known as EES (erythromycin ethylsuccinate, an ester prodrug that is commonly administered). In structure, this macrocyclic compound contains a 14-membered lactone ring with ten asymmetric centers and two sugars (L-cladinose and D-desosamine), making it a compound very difficult to produce via synthetic methods.

 

ARICEPT (donepezil HCl) is a prescription medicine to treat mild Alzheimer’s disease (up to 10 mg/day) and moderate to severe Alzheimer’s disease (up to 23 mg/day). Before starting on ARICEPT 23 mg/day, patients should be on ARICEPT 10 mg/day for at least 3 months. The starting dose of ARICEPT is 5 mg/day and can be increased to 10 mg/day after 4-6 weeks. Please take ARICEPT as prescribed by the doctor.
Antabuse, or disulfiram as it is also known, was the first medicine approved for the treatment of alcohol abuse and alcohol dependence by the U.S. Food and Drug Administration. Antabuse is prescribed to help people who want to quit drinking by causing a negative reaction if the person drinks while they are taking antabuse.

 

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